Tropical Journal of Pharmaceutical Research

Review Article | OPEN ACCESS

Ethno-pharmacological review on the wild edible medicinal plant, Lilium martagon L

Dmitry Olegovich Bokov^1,2 , Aleksandr Nikolaevich Luferov¹, Ivan (Jnr) Ivanovich Krasnyuk³, Vladimir Vladimirovich Bessonov²

¹Sechenov First Moscow State Medical University, Department of Pharmaceutical and Natural Sciences, 8, Trubetskaya St, Moscow 119991; ²Federal Research Center for Nutrition, Biotechnology and Food Safety, Laboratory of Food Chemistry, 2/14, Ustyinsky Pr, Moscow 109240; ³Sechenov First Moscow State Medical University, Department of Analytical, Physical and Colloid Chemistry, 8, Trubetskaya St, Moscow 119991, Russian Federation.

For correspondence:- Dmitry Bokov Email: fmmsu@mail.ru Tel:+79253588427

Accepted: 27 June 2019 Published: 29 July 2019

Citation: Bokov DO, Luferov AN, Krasnyuk II, Bessonov VV. Ethno-pharmacological review on the wild edible medicinal plant, Lilium martagon L. Trop J Pharm Res 2019; 18(7):1559-1564 doi: 10.4314/tjpr.v18i7.29

© 2019 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose: Martagon lily (Lilium martagon L.) is used in Eastern traditional medicine for wound healing and treatment of toothache. This review is intended to provide a comprehensive and critical evaluation of the chemical, botanical, ethnological, pharmacological, and pharmacognostic aspects of L. martagon, with a view to facilitating further in-depth pharmaceutical studies on the potentials of the plant as a herbal remedy.

Methods: Diverse electronic search engines and specialized reference tools such as Google, Google Scholar, Scopus, Web of Science, scientific literature, publishing sites and electronic databases (Pubmed, Springer, Wiley and Science Direct) were used for data retrieval. The data focused on botany, traditional uses, biological activities and phytochemistry of L. martagon, with emphasis on integration of this plant in official medicare.

Results: Lilium martagon possesses anti-inflammatory, sedative, anticancer, analgesic and hemostatic properties. Some modern techniques (in vitro propagation, genetic manipulation and advanced molecular biology techniques) have been applied in L. martagon biotechnology, with respect to major plant diseases and genetic variation issues.

Conclusion: Lilium martagon L contains different groups of biologically-active substances, amongst which are pyrroline derivatives and steroidal saponins. These may justify the usage of this plant and its subspecies in the traditional treatment of a wide spectrum of diseases.

Keywords: Lilium martagon, Pyrroline derivatives, Lilidine, Jatropham, Steroidal saponins, ^7;-methylene glutainic acid